K9 Advantix® II Flea, Tick and Mosquito Prevention for Dogs

For over 20 years, dog owners have trusted the K9 Advantix® brand to kill and repel fleas, ticks and mosquitoes too. 

With one easy-to-apply topical treatment, K9 Advantix® II works all month to kill pests through contact so they don’t have to bite your pet to die. Just select your dog’s weight, your preferred dosage and buy now.

k9 advantix: K9 Advantix® II flea, tick and mosquito prevention for dogs

  • Sale! Sale!
    K9 Advantix II Small Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 4-10 lbs.
    K9 Advantix II Small Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 4-10 lbs.
    Original price was: $79.98.Current price is: $58.98.
  • Sale! Sale!
    K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs.
    K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs.
    Original price was: $79.98.Current price is: $58.98.
  • Sale! Sale!
    K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs.
    K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21-55 lbs.
    Original price was: $79.98.Current price is: $58.98.
  • Sale! Sale!
    K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Over 55 lbs.K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Over 55 lbs.
    K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Over 55 lbs.
    Original price was: $79.98.Current price is: $58.98.

K9 Advantix® II | Flea, Tick and Mosquito Repellent for Dogs

Why choose K9 Advantix® II flea, tick and mosquito treatment?

K9 Advantix® II : Quickly kills and repels

Quickly kills and repels

Starts to kill fleas, ticks and mosquitoes within 12 hours — half the time of other leading brands.

K9 Advantix® II : Vet recommended

Vet recommended

No prescription needed. Effective on dogs and puppies 7 weeks of age and older that weigh 4 or more pounds.
K9 Advantix® II : Easy to apply

Easy to apply

Goes on in seconds. Apply drops directly on your dog’s skin — no hard-to-swallow pills.
K9 Advantix® II : Easy to apply

30 days of waterproof protection

K9 Advantix® II becomes waterproof after 24 hours and stays that way all month long.

How to Apply K9 Advantix® II Flea, Tick and Mosquito Treatment?

Ultimate Guide to K9 Advantix II for Dogs

Meet Dog’s Most Trusted Flea and Tick Repellent: K9 Advantix II for Dogs!

K9 Advantix II for Dogs is a vet-recommended formula designed to provide complete pest protection for your canine companion. This great product is perfect for outdoor dogs of all sizes, offering a powerful solution against fleas, ticks, lice, mosquitoes, and biting flies.

Key Features

  • Effective Against Fleas and Ticks: K9 Advantix II is highly effective in killing adult fleas, flea eggs, and existing flea infestations. This topical prevention solution also provides excellent tick prevention, reducing the risk of Lyme disease.

  • Kills and Repels Multiple Pests: This advanced formula not only kills fleas, ticks, and lice but also repels mosquitoes and biting flies, ensuring your dog stays comfortable and protected from various pests.

  • Easy Application: The easy application process involves using the applicator tube to gently squeeze the solution onto your dog’s skin, spreading the entire contents evenly. The blue box is designed for medium dogs, while the red box is suited for large dogs and extra-large dogs.

  • Vet-Recommended Formula: Trusted by veterinarians, K9 Advantix II uses active ingredients like permethrin to ensure maximum effectiveness against pests while being safe for your dog.

Benefits

  • Prevents Skin Irritation: By killing and repelling pests, K9 Advantix II helps prevent skin irritation, scratching, and discomfort in your dog.

  • Fragrance-Free and Gentle: This fragrance-free formula is gentle on your dog’s skin, reducing the risk of irritation around sensitive areas like the eyes and tail.

  • Long-Lasting Protection: One application provides protection for up to four weeks, making it a convenient and effective solution for ongoing pest prevention.

  • Safe for Multiple Animals: Unlike some treatments, K9 Advantix II is safe for other animals in your household, ensuring comprehensive pest protection without causing harm to your pets.

Usage Instructions

  1. Initial Application: For the first application, ensure your dog is dry. Part the hair at the base of the dog’s neck until the skin is visible.

  2. Apply: Place the applicator tube tip directly on the skin and gently squeeze to apply the entire contents in one spot. For large dogs, apply in multiple spots down the back.

  3. Avoid Excessive Amount: Ensure the solution is applied evenly without using an excessive amount. Avoid contact with your dog’s eyes and mouth.

  4. Wait for Effectiveness: Allow the treatment to work without bathing your dog or using shampoo immediately after application.

Additional Information

  • No Prescription Needed: K9 Advantix II is available without a prescription, making it easy for dog owners to access and use.

  • Great for Various Sizes: Whether you have a medium dog, large dog, or extra-large dog, K9 Advantix II offers tailored protection for your pet.

  • Suitable for All Breeds: This product is suitable for all breeds, providing comprehensive protection against pests.

  • Alternative to Flea Collars and Pills: K9 Advantix II serves as an excellent alternative to traditional flea collars and pills, offering easy topical prevention.

K9 Advantix II for Dogs is a veterinarian-approved dog medication with three strong, active ingredients to protect your dogs from fleas, ticks, mosquitoes, and lice. K9 Advantix II for Dogs is a once-a-month spot-on topical treatment that remains effective for the next four weeks after application.

The K9 Advantix II for Dogs Guarantee: External parasites and other insects don’t stand a chance against your lovable (and prepared) pup!

How does K9 Advantix II for Dogs work?

K9 Advantix II for Dogs is made up of strong three active ingredients to make it an effective once-a-month flea, tick, and mosquito treatment to prevent, repel, and kill pesky parasites: Imidacloprid, Permethrin, and Pyriproxyfen.

Imidacloprid is the world’s most used insecticide. Once the blood-sucking flea bites your dog, K9 Advantix II for Dogs attacks their central nervous system causing paralysis and its imminent death. Permethrin is the same but for ticks on contact. Pyriproxyfen (IGR) regulates the growth of flea larvae and at any stage of the flea life cycle.

How is K9 Advantix II for Dogs administered?

K9 Advantix II for Dogs is a topical formula that uses the spot-on treatment approach that is effective for the next four weeks after treatment. Proper spot-on treatment is packaged in individual doses of liquid and is applied by pouring the liquid onto the back of your pet.

Apply K9 Advantix II for Dogs 3 to 4 spots along the dog’s spine from between the shoulder blades to the base of the tail. Use one-third to one-fourth of the tubes’ contents in each spot applied on the dog’s skin. See the chart below to know the specific dosage for your dog:

Weight Dosage
10 lbs. and under 0.4 mL (Green)
11 lbs. – 20 lbs. 1.0 mL (Teal)
21 lbs. – 55 lbs. 2.5 mL (Red*)
55 lbs. + 4.0 mL (Blue*)

*Use several spots for a larger animal to avoid irritation.

 

Though the solution is waterproof, wait for a few hours to pet or bathe your dog. Once the solution is dry, You don’t need to reapply after bathing or swimming.

 

Which dogs should not use K9 Advantix II for Dogs?

Pregnant and lactating dogs. Puppies under 7 weeks old. Elderly dogs or those who are in a debilitated state. Be aware if your dog is allergic to any of the active ingredients. Lastly, keep out of reach of children or cats. The active ingredient permethrin is indigestible to cats.

What are the potential side effects of which you should be aware?

After the application of K9 Advantix II for Dogs, your furry best friend commonly experiences itching, burning, or numbness of their skin. If pain persists after a few hours, call your vet. If irritation persists after 3 days, call your vet.

Frequently Asked Questions
  1. What is the difference between K9 Advantix II large dogs vs. small dogs?

    All formulas have the same percentages of the active ingredients (8.8% Imidacloprid, 44% Permethrin, 0.44% Pyriproxyfen, and 46.76% other ingredients), but small dogs, medium dog, large dogs, and extra-large dogs require a different dosage depending on the dog’s weight (see chart above).

  2. What are the K9 Advantix reviews?

    K9 Advantix II for Dogs reviews gives the solution 4.5+ stars out of 5. Most reviewers say that they are long time users of this excellent product that ensure that there ain’t no bugs on their furry best friend. Reach out to your vet if having any concerns or questions about your dog’s use of K9 Advantix II for Dogs.

  3. How long does it take for K9 Advantix II to work on fleas and ticks?

    K9 Advantix II for Dogs kills fleas and ticks within 12 hours after application. In terms of new fleas, these parasites that newly bite your dog dies within 2 hours. K9 Advantix II for Dogs kills fleas and prevents infestations throughout the following four weeks.

  4. Is K9 Advantix II for puppies?

    K9 Advantix II for Dogs can be administered to puppies that are at least 7 weeks old.

  5. What is K9 Advantix II for Dog’s active ingredients?

    Imidacloprid is the world’s most used insecticide. Once the blood-sucking flea bites your dog, it attacks their central nervous system causing paralysis and its imminent death. Permethrin is the same but for ticks on contact. Pyriproxyfen is an insect growth regulator that regulates the growth of all fleas at any stage of the life cycle.

  6. What are the K9 Advantix side effects?

    Irritation is very common after the application. However, call your vet if the irritation persists for longer than 3 days, and if the pain lasts for longer than a few hours.

  7. Is K9 Advantix II for Dogs used for cats?

    No. K9 Advantix and K9 Advantix II for Dogs is for dogs only. Cats cannot digest the active ingredient Permethrin (i.e., treatment for ticks). They should even be kept away from K9 Advantix-treated dogs for 24 hours.

    However, with the two other active ingredients (e.g., Imidacloprid and Pyriproxyfen), Advantage II for Cats is a formula for once-a-month topical flea prevention and treatment for cats that effectively breaks the flea life cycle to prevent future infestations. The cat must be a minimum of 8 weeks old and a weight of 9 pounds.

Concluding Thoughts

The most important thing that you should know about K9 Advantix II for Dogs is its power to kill fleas, ticks, mosquitos, and lice on contact and prevent future infestations for 30 days after one application.

DISCLAIMER: Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427. This informative article is not meant to substitute for the diagnosis, treatment, and professional advice from your veterinarian or other qualified professionals regarding a medical condition.

Have your dog stand to ease the application process and evenly distribute the contents of one tube on 2-3 spots along their back, between their shoulders and the base of their tail. Part their hair so that skin is visible and gently squeeze the solution onto the skin. Make sure there is no excess dripping

Advantix is comprised of some of the most effective flea and tick repellants on the market – Imidacloprid, Permethrin, and Pyripoxyfen.

KEEP AWAY FROM CATS. Cats are unable to process the key ingredients in Advantix. They should be distanced from the dog for up to 24 hours after application. Some dogs may experience a burning, itching, tingling, or numbness of the skin after application. 

May cause a slight irritation on the point of contact, but this usually subsides within a few hours. If pain persists, contact a vet. Oral contact may cause salivation. If K9 Advantix gets into you or your dogs eyes, flush with water immediately.

This sensation usually subsides within 3 days, however if symptoms persist, consult your veterinarian.

Store Advantix in a cool, dry place. Keep out of reach of children or cats.

K9 Advantix is an effective, once a month flea & tick treatment that uses three types of medication (imidacloprid, permethrin, pyriproxyfen) to kill, prevent the growth of, and repel these pesky parasites. Imidacloprid is the most widely used insecticide in the world, attacking the central nervous system of fleas, while having little to no effect on mammals. Permethrin works in much the same way as imidacloprid, but against ticks, killing them on contact. Pyriproxyfen is an insect growth regulator (IGR), which means that it prevents flea larvae from further developing into adults, thereby stopping the flea life cycle in its tracks.

K9 Advantix is for dogs only. K9 Advantix should not be used in dogs that are in a debilitated state, elderly, pregnant, nursing, or under 7 weeks of age. Dogs that are taking other flea and tick medication should not be taking K9 Advantix, and dogs with a known allergy to any of the ingredients in K9 Advantix should not take this treatment. Cats should NEVER be given K9 Advantix, as they are unable to process permethrin. Contact to this medication by cats can be serious and even fatal. Cats should be kept away from dogs taking K9 Advantix up to 24 hours after being treated.

The proper way to apply K9 Advantix is to take the applicator tube out of its packaging and remove the cap, holding upright so as to not spill the contents. Depending on your dog’s weight, apply the solution in either 3 or 4 spots along their spine, between the shoulder blades and the base of their tail. Make sure to apply directly to the skin by ruffling their fur. Place a third to a quarter of the tubes contents in each of the spots of application, being careful to avoid dripping. Allow a few hours for the solution to dry before petting or bathing. The solution is waterproof, so once dry, there is no need to reapply if your dog decides to go swimming or is in need of a bath.

Ask your veterinarian or consult with one of our pet care specialists at 1-800-844-1427.

This information is for informational purposes only and is not meant as a substitute for the professional advice of, or diagnosis or treatment by, your veterinarian. Always seek the advice of your veterinarian or other qualified professional with any questions you may have regarding a medical condition. Never disregard or delay seeking professional advice due to what you may have read on our website. Our medications are FDA approved and/or EPA regulated when and as required by law.

Top questions about K9 Advantix® II

Not all products work the same way: K9 Advantix® II is applied to the pet’s skin, spreading the active ingredients over your dog’s body to kill fleas, ticks and mosquitoes through contact. No biting required!

A single application of K9 Advantix® II keeps working for a month.

Use only on dogs. DO NOT USE ON CATS or other animals. Do not apply to dogs weighing less than 4 lbs. Remove applicator tube from the package. Use scissors and peel down foil. Hold applicator tube in an upright position. Pull cap off tube. Turn the cap around and place other end of cap back on tube. Twist cap to break seal, then remove cap from tube. The dog should be standing for easy application. Evenly apply the entire contents of the tube along the top of the dog’s back, from the shoulder down to the base of the tail. The number of spots depends on the size and weight of your dog (please refer to the product label). At each spot, part the hair until the skin is visible. Place the tip of the tube on the skin and gently squeeze to expel a portion of the solution on the skin. Do not apply an excessive amount of solution at any one spot that could cause some of the solution to run off the side of the dog. Do not get this product in your dog’s eyes, or allow your dog to ingest this product.
Can my dog go swimming after using K9 Advantix® II? Yes! Your dog is free to take a dip after K9 Advantix® II has been on for 24 hours.

Please consult your dog’s veterinarian for their recommendation.

Yes! We suggest bathing your dog before applying K9 Advantix® II. Your dog needs to be dry at the time of application. If you choose to bathe your dog in between treatments, we recommend use of a general grooming shampoo for pets.

A single application of K9 Advantix® II remains effective for four weeks. However, if the dog has a severe infestation, retreatment within a month may be necessary. Do not retreat more than once every seven days, not to exceed 4 weekly treatments. After flea control is attained, return to a monthly treatment schedule. 

Although K9 Advantix® II kills fleas on your dog, there may still be fleas in your dog’s environment that have since jumped on after treatment. Luckily, with K9 Advantix® II, new fleas are killed within 2 hours with protection against further infestation for at least 4 weeks. As fleas die they are no longer able to stay hidden against your dog’s skin, and therefore you may also be seeing dying fleas coming to the surface of your dog’s fur coat.

K9 Advantix® II kills fleas within 12 hours. New fleas that jump on the dog from the surroundings, such as grass, carpet and pet bedding, are killed within 2 hours with protection against further infestation for at least 4 weeks.

Yes! Your dog is free to take a dip after K9 Advantix® II has been on for 24 hours. More frequent swimming may keep the product from working for the full 30 days.

Monitor your dog after application. In rare cases, some side effects may include signs of skin irritation such as redness, scratching or other signs of discomfort. Gastrointestinal signs such as vomiting or diarrhea have also been reported. If these or other side effects (such as lethargy or agitation) occur, consult your veterinarian or call 800-422-9874.

Proper administration of effective residual flea products to all dogs and cats means no more fleas reproducing and no more eggs dropping into the environment.

Therefore, within 2 to 7 days, eggs that were previously deposited have developed into larvae, within 1 to 2 weeks the larvae have now developed into pupae, and 1 to 4 weeks later those pupae are now adult fleas. As these fleas emerge and jump on treated pets they are hopefully being killed by the flea product.

Therefore within 3 to 8 weeks or occasionally as long as 3 months, all the adult fleas and immature life stage biomass should be gone.6,7 How bad a flea i

SAFETY INFORMATION

 
Do not use K9 Advantix® II on cats.
K9 Advantix, Elanco and the diagonal bar logo are trademarks of Elanco or its affiliates.

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